NEW YORK (CNNMoney.com) — Warren Buffett’s Berkshire Hathaway said Tuesday it will buy railroad operator Burlington Northern Santa Fe for $44 billion.

Berkshire (BRKA, Fortune 500), which already has major stake in Burlington Northern, said it would acquire the remaining 77.4% of the company in a cash-and-stock offer worth $100 per share.

Widely regarded as both one of the world’s richest men and the investment community’s more brilliant minds, Buffett called his firm’s investment an “all-in wager on the economic future of the United States.”

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